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Atlas of differential diagnosis in neoplastic hematopathology

Gorczyca, Wojciech

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개인저자Gorczyca, Wojciech,,1959-,,author.
서명/저자사항Atlas of differential diagnosis in neoplastic hematopathology : Wojciech Gorczyca.
판사항Third edition.
발행사항Boca Raton:Taylor & Francis/CRC Press,2014.
형태사항xv, 903 p.; :ill.,photo. ;30 cm.
ISBN9781482212211 (hardcover : alk. paper) :
서지주기Includes bibliographical references and index.
요약"Preface The field of neoplastic hematology is changing rapidly and the management of patients relies more than ever on morphologic, immunophenotypic, karyotypic, and genetic characteristics We are witnessing the emergence of truly individualized approaches to treatment; therefore, morphologic and even extensive immunophenotypic analyses of tumors are not sufficient anymore, as diagnosis, prognosis, and treatment strategies depend heavily on the molecular makeup of tumors Acute myeloid leukemias (AMLs) are now classified based on specific chromosomal changes and mutational status of an expanding list of genes The prognosis of patients with AML cannot be established by a single methodology such as metaphase cytogenetics or even evaluation of the mutation of one gene [e g , concomitant KIT mutations occurring in the context of core-binding factor-positive AML confer a negative prognosis and NPM1+ AML has a good prognosis only if associated with wild-type fms-related tyrosine kinase 3 gene (FLT3)] The list of mature B- and T-cell lymphoproliferations, both nodal and extranodal, continues to expand and includes (among others) "gray zone" lymphomas (double-hit lymphomas), T-cell lymphomas with a follicular T-helper phenotype, and numerous morphologic and immunophenotypic variants of diffuse large B-cell lymphoma Myeloproliferative neoplasms are classified based on the status of JAK2, BCR-ABL1, KIT, and PDGFRA, with morphologic analysis of the bone marrow still playing a crucial role Flow cytometric analysis with 6-, 8-, or even 10-color methodologies helps in the diagnosis and subclassification of acute leukemias as well as B- and T-cell lymphomas, but is also expanding its role in patients with myelodysplastic syndrome (MDS) or myeloproliferative neoplasms"--Provided by publisher.
일반주제명Hematologic Neoplasms -- diagnosis -- Atlases.
Diagnosis, Differential -- Atlases.
Leukemia -- Atlases.
Lymphoma -- Atlases.
Myeloproliferative Disorders -- Atlases.
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No. 등록번호 청구기호 소장처/자료실/서가 도서상태 반납예정일 예약
1 80002938 616.99418 G66at3 화순전남대학교병원/의학도서실/ 대출가능