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Orthobiologics Injectable Therapies for the Musculoskeletal System [electronic resource]
Filardo, Giuseppe
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| 자료유형 | 단행본 |
|---|---|
| 개인저자 | Filardo, Giuseppe.,editor. Mandelbaum, Bert R.,editor. Muschler, George F.,editor. Rodeo, Scott A.,editor. Nakamura, Norimasa.,editor. |
| 단체저자명 | SpringerLink (Online service). |
| 서명/저자사항 | Orthobiologics [electronic resource] : Injectable Therapies for the Musculoskeletal System / edited by Giuseppe Filardo, Bert R. Mandelbaum, George F. Muschler, Scott A. Rodeo, Norimasa Nakamura. |
| 판사항 | 1st ed. 2022. |
| 형태사항 | XI, 402 p. 73 illus., 66 illus. in color:online resource. |
| 기본자료 저록 | Springer Nature eBook |
| 기타형태 저록 | Printed edition:9783030847432Printed edition:9783030847456Printed edition:9783030847463 |
| ISBN | 9783030847449 |
| 기타표준부호 | 10.1007/978-3-030-84744-9 |
| 내용주기 | I. Injectable OrthoBiologics: Formulations and Rationale 1. Bone marrow-derived cultured stromal cells and Bone Marrow Concentrate -- 2. Adipose-derived cultured stromal cells and Stromal Vascular Fraction from adipose tissue -- 3. Synovial-derived cultured stromal cells -- 4. Amniotic, Placenta, and Umbilical cord-derived cultured stromal cells -- 5. Allogeneic cells: pros and cons -- 6. Steroid hormones -- 7. Cytokines, chemokines, alpha-2-macroglobulin, growth factors -- 8. Platelet-rich plasma: leucocyte-rich, leukocyte-poor, autologous conditioned serum, autologous protein solution -- 9. Amniotic tissue extract, placenta tissue extract -- 10. Extracellular vesicles (exosomes) -- II. Injectable OrthoBiolologics: evaluation methods and results based on pathology and anatomy -- 11. Rotator cuff tendinopathy: cell therapy -- 12. Rotator cuff tendinopathy: biologics -- 13. Tennis elbow: cell therapy -- 14. Tennis elbow: cell therapy biologics -- 15. Patellar tendinopathy: cell therapy -- 16. Patellar tendinopathy: biologics -- 17. Achilles tendinopathy: cell therapy -- 18. Achilles tendinopathy: biologics -- 19. Plantar Fasciitis: cell therapy -- 20. Plantar Fasciitis: biologics -- 21. Ligament lesions: cell therapy -- 22. Ligament lesions: biologics -- 23. Meniscal lesions: cell therapy -- 24. Meniscal lesions: biologics -- 25. Muscle lesions: cell therapy -- 26. Muscle lesions: biologics -- 27. Fractures (incl. Nonunions): cell therapy -- 28. Fractures (incl. Nonunions): biologics -- 29. Cartilage lesions and Osteoarthritis of the knee: cell therapy -- 30. Cartilage lesions and Osteoarthritis of the knee: biologics -- 31. Cartilage lesions and Osteoarthritis of the hip and ankle: cell therapy -- 32. Cartilage lesions and Osteoarthritis of the hip and ankle: biologics -- III. Future directions 33. Pluripotent stem cells: Embryonic/Fetal stem cells and induced pluripotent stem (iPS) cells -- 34. Gene therapy -- 35. Stimulation of the intrinsic stromal cell niche -- 36 Conclusions. |
| 요약 | This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts. |
| 일반주제명 | Orthopedics. Sports medicine. Regenerative medicine. Medical sciences. Orthopaedics. Sports Medicine. Regenerative Medicine and Tissue Engineering. Health Sciences. |
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