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Molecular Diagnosis and Targeting for Gynecologic Malignancy [electronic resource]
Isonishi, Seiji
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| 자료유형 | 단행본 |
|---|---|
| 개인저자 | Isonishi, Seiji.,editor. Kikuchi, Yoshihiro.,editor. |
| 단체저자명 | SpringerLink (Online service). |
| 서명/저자사항 | Molecular Diagnosis and Targeting for Gynecologic Malignancy [electronic resource] / edited by Seiji Isonishi, Yoshihiro Kikuchi. |
| 판사항 | 1st ed. 2021. |
| 형태사항 | VIII, 165 p. 26 illus., 24 illus. in color:online resource. |
| 총서사항 | Current Human Cell Research and Applications=2522-0748 |
| 총서부출표목 | Current Human Cell Research and Applications, |
| 기본자료 저록 | Springer Nature eBook |
| 기타형태 저록 | Printed edition:9789813360129Printed edition:9789813360143Printed edition:9789813360150 |
| ISBN | 9789813360136 |
| 기타표준부호 | 10.1007/978-981-33-6013-6 |
| 내용주기 | 1 Cancer Stem Cells in gynecologic cancer -- 2 Patient-derived xenograft models in gynaecological malignancies -- 3 Cancer genomic profiling of gynecological malignancies by Todai OncoPanel, a twin DNA and RNA panel -- 4 Investigating the molecular carcinogenesis of ovarian high-grade serous cancer -- 5 The role of G protein-coupled receptor signaling in gynecologic malignancy -- 6 Tailor-made therapy according genetic alteration in epithelial ovarian cancers -- 7 Signaling and drug resistance -- 8 Molecular analysis in endometrial carcinoma -- 9 Molecular Landscape in Ovarian Clear Cell Carcinoma -- 10 Molecular pathology and clinicopathological significance of endometrial carcinoma -- 11 Novel approach for therapeutics of cervical cancer based on HPV-associated carcinogenesis at the cervix -- 12 Hereditary gynecological malignancy and molecular features. |
| 요약 | This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment , exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases. |
| 일반주제명 | Oncology. Gynecology . Cancer. Cytology. Oncology. Gynecology. Cancer Biology. Cell Biology. |
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