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Tumor Liquid Biopsies [electronic resource]

Schaffner, Florence

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개인저자Schaffner, Florence.,editor.
Merlin, Jean-Louis.,editor.
von Bubnoff, Nikolas.,editor.
단체저자명SpringerLink (Online service).
서명/저자사항Tumor Liquid Biopsies [electronic resource] / edited by Florence Schaffner, Jean-Louis Merlin, Nikolas von Bubnoff.
판사항1st ed. 2020.
형태사항VI, 368 p:online resource.
총서사항Recent Results in Cancer Research=2197-6767 ;215
총서부출표목Recent Results in Cancer Research,215
기본자료 저록Springer Nature eBook
기타형태 저록Printed edition:9783030264383Printed edition:9783030264406Printed edition:9783030264413
ISBN9783030264390
기타표준부호10.1007/978-3-030-26439-0
내용주기Circulating Tumor Cells: Pathophysiology of Tumor Cell Release into the Circulation and characterization of CTC -- CTC enrichment technologies -- Genotyping of CTC :example Lung cancer -- CTC in Breast Cancer: a clinical approach -- Circulating Tumor DNA: Pathophysiology of ctDNA Release into the Circulation and its characterization -- Enrichment and Analysis of ctDNA -- ctDNA in Lung Cancer -- ctDNA in Breast Cancer -- ctDNA in Colorectal Cancer -- Dynamic Treatment Stratification using ctDNA -- Circulating Tumor RNA: Noncoding Tumor RNAs: Pathophysiology of Release and Techniques of Detection -- Circulating miRNAs as Biomarker in Cancer -- Plasma Subcompartments as Source for Tumor derived Biomarkers: Exosomes and Vesicles as Biomarker in Cancer -- Quantitative proteomic Analysis of Plasma in Cancer.
요약This book is a comprehensive guide to the techniques, clinical applications, and benefits of the different forms of liquid biopsy employed in patients with a variety of tumor types, including lung, breast and colorectal cancer. Offering detailed explanations, it discusses the how changes in tumors can be tracked using these cutting-edge technologies, which enable the detection and analysis of diverse circulating biomarkers: tumor cells, tumor DNA, tumor RNA (free or in exosomes), and fluid biomarkers identifiable by means of targeted proteomics. The use of such advanced technologies is enabling us to tackle questions and problems in a way that was not possible just a few years ago. We now have at our disposal an effective means of overcoming the problem of intratumor heterogeneity, which has limited the value of conventional biopsy approaches. As a consequence, oncology practice is about to change radically, toward truly personalized precision medicine. This book provides both clinicians and researchers with a thorough and up-to-date overview of progress in the field.
일반주제명Oncology.
Pathology.
Cancer.
Oncology.
Pathology.
Cancer Biology.
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