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Biology and Treatment of Leukemia and Bone Marrow Neoplasms [electronic resource]
Pullarkat, Vinod
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| 자료유형 | 단행본 |
|---|---|
| 개인저자 | Pullarkat, Vinod.,editor. Marcucci, Guido.,editor. |
| 단체저자명 | SpringerLink (Online service). |
| 서명/저자사항 | Biology and Treatment of Leukemia and Bone Marrow Neoplasms [electronic resource] / edited by Vinod Pullarkat, Guido Marcucci. |
| 판사항 | 1st ed. 2021. |
| 형태사항 | VIII, 196 p. 17 illus., 14 illus. in color:online resource. |
| 총서사항 | Cancer Treatment and Research=2509-8497 ;181 |
| 총서부출표목 | Cancer Treatment and Research,181 |
| 기본자료 저록 | Springer Nature eBook |
| 기타형태 저록 | Printed edition:9783030783105Printed edition:9783030783129Printed edition:9783030783136 |
| ISBN | 9783030783112 |
| 기타표준부호 | 10.1007/978-3-030-78311-2 |
| 내용주기 | Advances in diagnosis and risk stratification of leukemias and bone marrow neoplasms -- Genetics and diagnostic approach to lymphoblastic leukemia -- Acute promyelocytic leukemia: update on risk stratification and treatment -- Current and emerging therapies for AML -- Current management and new developments in treatment of ALL -- Contemporary therapy of CML -- MDS: Pathogenesis and therapy -- Chronic lymphocytic leukemia: Biology and therapy -- Biology and current treatment of Myeloproliferative neoplasms -- Systemic Mastocytosis: Pathology and treatment -- Adoptive T-cell therapy and other novel immunotherapies for leukemia. |
| 요약 | This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students. |
| 일반주제명 | Hematology. Oncology. Medicine—Research. Biology—Research. Hematology. Oncology. Biomedical Research. |
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