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Hematologic Malignancies Case Studies in Cytogenetic and Molecular Genetics [electronic resource]
Bhargava, Manorama
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| 자료유형 | 단행본 |
|---|---|
| 개인저자 | Bhargava, Manorama.,author. |
| 단체저자명 | SpringerLink (Online service). |
| 서명/저자사항 | Hematologic Malignancies [electronic resource] : Case Studies in Cytogenetic and Molecular Genetics / by Manorama Bhargava. |
| 판사항 | 1st ed. 2021. |
| 형태사항 | XXVI, 246 p. 232 illus., 114 illus. in color:online resource. |
| 기본자료 저록 | Springer Nature eBook |
| 기타형태 저록 | Printed edition:9789813347984Printed edition:9789813348004Printed edition:9789813348011 |
| ISBN | 9789813347991 |
| 기타표준부호 | 10.1007/978-981-33-4799-1 |
| 내용주기 | Techniques in Cytogenetics -- Techniques in Molecular Haematology -- Part: I - Case Studies in Myeloid Malignancies -- Acute Myeloid Leukemia -- Myelodysplastic Syndrome -- Myelodysplastic Syndromes - Myeloproliferative Neoplasms -- Myeloproliferative Neoplasms -- Chronic Myeloid Leukemia -- Next Generation Sequencing for Diagnostics of Myeloid Malignancies for Routine Clinical Use: Pitfalls and Advantages -- Part: II - Case Studies in Lymphoid Malignancies -- Acute Lymphoblastic Leukemia -- Chronic Lymphocytic Leukemia and Non Hodgkin’s Lymphoma -- Part: III - Case Studies in Multiple Myeloma -- Multiple Myeloma. |
| 요약 | This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well. |
| 일반주제명 | Hematology. Molecular genetics. Pathology. Hematology. Molecular Genetics. Pathology. |
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