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Humoral Primary Immunodeficiencies [electronic resource]
D'Elios, Mario Milco
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| 자료유형 | 단행본 |
|---|---|
| 개인저자 | D'Elios, Mario Milco.,editor. Rizzi, Marta.,editor. |
| 단체저자명 | SpringerLink (Online service). |
| 서명/저자사항 | Humoral Primary Immunodeficiencies [electronic resource] / edited by Mario Milco D'Elios, Marta Rizzi. |
| 판사항 | 1st ed. 2019. |
| 형태사항 | X, 387 p. 34 illus. in color:online resource. |
| 총서사항 | Rare Diseases of the Immune System=2283-6403 |
| 총서부출표목 | Rare Diseases of the Immune System, |
| 기본자료 저록 | Springer Nature eBook |
| 기타형태 저록 | Printed edition:9783319917849Printed edition:9783319917863 |
| ISBN | 9783319917856 |
| 기타표준부호 | 10.1007/978-3-319-91785-6 |
| 내용주기 | Preface -- 1. B cells and the B-cell immunological synapse.-2 Mucosal B cells -- 3 CVID. – 4 LOCID. – 5 Genetics of CVID. – 6 ICOS deficiency. – 7 CD19 deficiency -- 8 CD20 deficiency. – 9 CD21 deficiency. – 10 CD81 deficiency. - 11 TACI deficiency, . – 12 LRBA deficiency. – 13 BAFF receptor deficiency. – 14 TWEAK defects. - 15 NFKB2 deficiency. – 16 WHIM syndrome. – 17 Novel humoral PID genes. – 18 Class Switch Recombination defects, -- 19 Selective IgA deficiency -- 20 IgA with IgG subclass deficiency. - 21 Isolated IgG subclass deficiency. – 22 Thymoma with immunodeficiency. – 23 PRKC delta and PI3K-delta associated diseases. – 24 Differential diagnostic in hypogammaglobulinemia. – 25 Management of Humoral primary immunodeficiencies in pediatrics -- 26 Management of Humoral primary immunodeficiencies in adults -- 27 Vaccines in humoral PID -- 28 Humoral PID and neoplasias -- 29 Humoral PID and autoimmunity. – 30 Lung involvement -- 31 Gut involvement -- Subject Index. |
| 요약 | This book presents detailed state of the art knowledge on the humoral primary immunodeficiencies (PIDs), i.e., disorders arising from impaired antibody production due to defects intrinsic to B cells or defective interaction between B and T cells. There is extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the B cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel humoral PID genes and related clinical applications, mucosal B cells, and the various clinical phenotypes of humoral PIDs. Aspects such as differential diagnosis, clinical management in children and adults, and the role of vaccines are also addressed. The authors are all recognized experts from Europe, Australia, and the United States. Humoral Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD and PhD students. |
| 일반주제명 | Rheumatology. Immunology. Diseases. Oncology. Rheumatology. Immunology. Diseases. Oncology. |
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