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Current Immunotherapeutic Strategies in Cancer [electronic resource]
Theobald, Matthias
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| 자료유형 | 단행본 |
|---|---|
| 개인저자 | Theobald, Matthias.,editor. |
| 단체저자명 | SpringerLink (Online service). |
| 서명/저자사항 | Current Immunotherapeutic Strategies in Cancer [electronic resource] / edited by Matthias Theobald. |
| 판사항 | 1st ed. 2020. |
| 형태사항 | V, 187 p:online resource. |
| 총서사항 | Recent Results in Cancer Research=2197-6767 ;214 |
| 총서부출표목 | Recent Results in Cancer Research,214 |
| 기본자료 저록 | Springer Nature eBook |
| 기타형태 저록 | Printed edition:9783030237646Printed edition:9783030237660Printed edition:9783030237677 |
| ISBN | 9783030237653 |
| 기타표준부호 | 10.1007/978-3-030-23765-3 |
| 내용주기 | Current Development of Monoclonal Antibodies in Cancer Therapy -- Clinical Experience with Bispecific T-Cell Engagers -- Advances and challenges of CAR-modified T cells in clinical trials -- Targeting Cancer with Genetically Engineered TCR-T Cells -- Tailored Vaccines Based on Patient’s Cancer Mutanome -- Next-Generation Checkpoint Inhibitors and Immune Agonists. |
| 요약 | This book offers a comprehensive review of recent advances in cancer immunotherapy, and explores the value and limitations of the most effective current therapeutic strategies and emerging treatment modalities. It discusses in detail the successes achieved using monoclonal antibodies (mAbs), including developments with regard to conjugated mAbs and also bispecific mAbs as novel treatment options for leukemia and solid tumors. It also examines the advances toward personalized immunotherapy, focusing on the effectiveness of adoptive cell therapy using genetically engineered T cells with tumor-associated antigen-specific T-cell receptors and chimeric antigen receptors, as well as the role of tailored vaccines based on the patient’s cancer mutanome. Further, it describes the impressive therapeutic results recently achieved with checkpoint inhibitors, and analyzes novel strategies to modulate the immunosuppressive tumor microenvironment. Written by leading international experts and providing up-to-date information on emerging strategies, such as oncolytic virus-based therapy, epigenetic therapy, and combination therapy, the book appeals to all those with an interest in immunotherapy as it comes of age. |
| 일반주제명 | Oncology. Immunology. Oncology. Immunology. |
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